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The germline HLA-A02B62 supertype is associated with a PD-L1-positive tumour immune microenvironment and poor prognosis in stage I lung cancer
BACKGROUND: Germline HLA class I molecule supertypes are shown to correlate with response to anti-PD-1 therapy. Here, we investigate the significance of germline HLA-A and HLA-B supertypes in tumour microenvironment of non-small-cell lung cancer. METHODS: Totally 278 NSCLC patients were collected re...
Autores principales: | Lin, Ruijiang, Chen, Xiaohua, Su, Fei, Wang, Hongbin, Han, Biao, Chen, Yanhui, Zhang, Cuixiang, Ma, Minjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432705/ https://www.ncbi.nlm.nih.gov/pubmed/37600368 http://dx.doi.org/10.1016/j.heliyon.2023.e18948 |
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