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Ligustrazine alleviates pulmonary arterial hypertension in rats by promoting the formation of myocardin transcription complex in the nucleus of pulmonary artery smooth muscle cells

Pulmonary arterial hypertension (PAH) is a pathophysiological state of abnormally elevated pulmonary arterial pressure caused by drugs, inflammation, toxins, viruses, hypoxia, and other risk factors. We studied the therapeutic effect and target of tetramethylpyrazine (tetramethylpyrazine [TMP]; ligu...

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Detalles Bibliográficos
Autores principales: Yu, Xichao, Wu, Mingjie, Meng, Qinhai, Zhu, Weijie, Zhang, Chenyan, Liu, Bowen, Qi, Yuewen, Gu, Shuqun, Wang, Xinyu, Wen, Jingli, Li, Yu, Qi, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432881/
https://www.ncbi.nlm.nih.gov/pubmed/37186419
http://dx.doi.org/10.1111/cts.13534