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Improving cellular phylogenies through the integrated use of mutation order and optimality principles

The study of tumor evolution is being revolutionalized by single-cell sequencing technologies that survey the somatic variation of cancer cells. In these endeavors, reliable inference of the evolutionary relationship of single cells is a key step. However, single-cell sequences contain many errors a...

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Detalles Bibliográficos
Autores principales: Miura, Sayaka, Dolker, Tenzin, Sanderford, Maxwell, Kumar, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432911/
https://www.ncbi.nlm.nih.gov/pubmed/37602230
http://dx.doi.org/10.1016/j.csbj.2023.07.018