Stress-induced pseudokinase TRB3 augments IL1β signaling by interacting with Flightless homolog 1

Interleukin-1β is one of the most potent inducers of beta cell inflammation in the lead-up to type 1 diabetes. We have previously reported that IL1β-stimulated pancreatic islets from mice with genetic ablation of stress-induced pseudokinase TRB3(TRB3KO) show attenuated activation kinetics for the MA...

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Detalles Bibliográficos
Autores principales: Gonuguntla, Sumati, Humphrey, Rohan K., Gorantla, Akshita, Hao, Ergeng, Jhala, Ulupi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432976/
https://www.ncbi.nlm.nih.gov/pubmed/37172723
http://dx.doi.org/10.1016/j.jbc.2023.104803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432976/
https://www.ncbi.nlm.nih.gov/pubmed/37172723
http://dx.doi.org/10.1016/j.jbc.2023.104803

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