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Metformin promotes cGAS/STING signaling pathway activation by blocking AKT phosphorylation in gastric cancer

The cGAS/STING signaling pathway plays a pivotal role in regulating innate immunity. Emerging novel drugs aim to regulate the anti-tumor immune response by activating innate immunity. The anti-diabetic drug metformin has been reported to exhibit anti-cancer effect against various types of cancer. Ho...

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Detalles Bibliográficos
Autores principales: Shen, Qian, Yang, Lei, Li, Chengguo, Wang, Tao, Lv, Jianbo, Liu, Weizhen, Lin, Yao, Yin, Yuping, Tao, Kaixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432977/
https://www.ncbi.nlm.nih.gov/pubmed/37600406
http://dx.doi.org/10.1016/j.heliyon.2023.e18954