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Carbonic anhydrase IX subcellular localization in normoxic and hypoxic SH-SY5Y neuroblastoma cells is assisted by its C-terminal protein interaction domain()

The human carbonic anhydrase IX (CA IX) is a hypoxia-induced transmembrane protein belonging to the α-CA enzyme family. It has a crucial role in pH regulation in hypoxic cells and acts by buffering intracellular acidosis induced by hypoxia. Indeed, it is frequently expressed in cancer cells, where i...

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Detalles Bibliográficos
Autores principales: Succoio, Mariangela, Amiranda, Sara, Sasso, Emanuele, Marciano, Carmen, Finizio, Arianna, De Simone, Giuseppina, Garbi, Corrado, Zambrano, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432983/
https://www.ncbi.nlm.nih.gov/pubmed/37600419
http://dx.doi.org/10.1016/j.heliyon.2023.e18885