Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms

BACKGROUND: Pharmacological synergisms are an attractive anticancer strategy. However, with more than 5000 approved-drugs and compounds in clinical development, identifying synergistic treatments represents a major challenge. METHODS: High-throughput screening was combined with target deconvolution...

Descripción completa

Detalles Bibliográficos
Autores principales: Ariey-Bonnet, Jérémy, Berges, Raphael, Montero, Marie-Pierre, Mouysset, Baptiste, Piris, Patricia, Muller, Kevin, Pinna, Guillaume, Failes, Tim W., Arndt, Greg M., Morando, Philippe, Baeza-Kallee, Nathalie, Colin, Carole, Chinot, Olivier, Braguer, Diane, Morelli, Xavier, André, Nicolas, Carré, Manon, Tabouret, Emeline, Figarella-Branger, Dominique, Le Grand, Marion, Pasquier, Eddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433015/
https://www.ncbi.nlm.nih.gov/pubmed/37572644
http://dx.doi.org/10.1016/j.ebiom.2023.104752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433015/
https://www.ncbi.nlm.nih.gov/pubmed/37572644
http://dx.doi.org/10.1016/j.ebiom.2023.104752

Ejemplares similares