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Interleukin-34-NF-κB signaling aggravates myocardial ischemic/reperfusion injury by facilitating macrophage recruitment and polarization

BACKGROUND: Macrophage infiltration and polarization are integral to the progression of heart failure and cardiac fibrosis after ischemia/reperfusion (IR). Interleukin 34 (IL-34) is an inflammatory regulator related to a series of autoimmune diseases. Whether IL-34 mediates inflammatory responses an...

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Detalles Bibliográficos
Autores principales: Zhuang, Lingfang, Zong, Xiao, Yang, Qian, Fan, Qin, Tao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433018/
https://www.ncbi.nlm.nih.gov/pubmed/37556943
http://dx.doi.org/10.1016/j.ebiom.2023.104744