New Thiazole Carboxamide Derivatives as COX Inhibitors: Design, Synthesis, Anticancer Screening, In Silico Molecular Docking, and ADME Profile Studies

[Image: see text] The goal of this work was to create and test a new series of thiazole carboxamide derivatives for their cyclooxygenase (COX) suppressor and anticancer effects. The compounds were characterized using 1H, 13C NMR, and HRMS spectrum analysis, and their selectivity toward COX-1 and COX...

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Detalles Bibliográficos
Autores principales: Hawash, Mohammed, Jaradat, Nidal, Sabobeh, Rozan, Abualhasan, Murad, Qaoud, Mohammed T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433355/
https://www.ncbi.nlm.nih.gov/pubmed/37599929
http://dx.doi.org/10.1021/acsomega.3c03256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433355/
https://www.ncbi.nlm.nih.gov/pubmed/37599929
http://dx.doi.org/10.1021/acsomega.3c03256

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