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Effect of Colchicine Binding Site Inhibitors on the Tubulin Intersubunit Interaction

[Image: see text] Microtubules are dynamic, non-covalent polymers consisting of α- and β-tubulin subunits that are involved in a wide range of intracellular processes. The polymerization and dynamics of microtubules are regulated by many factors, including small molecules that interact with differen...

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Detalles Bibliográficos
Autores principales: Sargsyan, Arsen, Sahakyan, Harutyun, Nazaryan, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433359/
https://www.ncbi.nlm.nih.gov/pubmed/37599936
http://dx.doi.org/10.1021/acsomega.3c02979