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The pharmacokinetic–pharmacodynamic modelling framework as a tool to predict drug resistance evolution

Pharmacokinetic–pharmacodynamic (PKPD) models, which describe how drug concentrations change over time and how that affects pathogen growth, have proven highly valuable in designing optimal drug treatments aimed at bacterial eradication. However, the fast rise of antimicrobial resistance calls for i...

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Detalles Bibliográficos
Autores principales: Witzany, Christopher, Rolff, Jens, Regoes, Roland R., Igler, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433423/
https://www.ncbi.nlm.nih.gov/pubmed/37522891
http://dx.doi.org/10.1099/mic.0.001368