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The pharmacokinetic–pharmacodynamic modelling framework as a tool to predict drug resistance evolution
Pharmacokinetic–pharmacodynamic (PKPD) models, which describe how drug concentrations change over time and how that affects pathogen growth, have proven highly valuable in designing optimal drug treatments aimed at bacterial eradication. However, the fast rise of antimicrobial resistance calls for i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433423/ https://www.ncbi.nlm.nih.gov/pubmed/37522891 http://dx.doi.org/10.1099/mic.0.001368 |