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Tetracaine hydrochloride induces macrophage pyroptosis through caspase‑1/11‑GSDMD signaling pathways

Tetracaine hydrochloride (TTC) is a long-lasting local anesthetic commonly used for topical anesthesia. Inappropriate dosage or allergic reactions to TTC can lead to local anesthetic toxicity. TTC exerts cytotoxic effects on certain cell types by inducing apoptosis and necrosis; however, the effects...

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Detalles Bibliográficos
Autores principales: Zhang, Ran, Gou, Wanrong, Yi, Peng, Qin, Zhengshan, Zhu, Danli, Jia, Jing, Liu, Li, Jiang, Xian, Feng, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433433/
https://www.ncbi.nlm.nih.gov/pubmed/37602302
http://dx.doi.org/10.3892/etm.2023.12127