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Physiologically Based Pharmacokinetic Model To Predict Metoprolol Disposition in Healthy and Disease Populations

[Image: see text] The evolution in the development of drugs has increased the popularity of physiologically based pharmacokinetic (PBPK) models. This study seeks to assess the PK of metoprolol in populations with healthy, chronic kidney disease (CKD), and acute myocardial infarction (AMI) conditions...

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Detalles Bibliográficos
Autores principales: Zamir, Ammara, Rasool, Muhammad Fawad, Imran, Imran, Saeed, Hamid, Khalid, Sundus, Majeed, Abdul, Rehman, Anees Ur, Ahmad, Tanveer, Alasmari, Fawaz, Alqahtani, Faleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433471/
https://www.ncbi.nlm.nih.gov/pubmed/37599939
http://dx.doi.org/10.1021/acsomega.3c02673