A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage

BACKGROUND: The development of nonapoptotic programmed cell death inducers as anticancer agents has emerged as a cancer therapy field. Ferroptosis, ferrous ion-driven programmed cell death that is induced by redox imbalance and dysfunctional reactive oxygen species (ROS) clearance, is triggered duri...

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Detalles Bibliográficos
Autores principales: Bow, Yung-Ding, Ko, Ching-Chung, Chang, Wen-Tsan, Chou, Sih-Yan, Hung, Chun-Tzu, Huang, Jau-Ling, Tseng, Chih-Hua, Chen, Yeh-Long, Li, Ruei-Nian, Chiu, Chien-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433610/
https://www.ncbi.nlm.nih.gov/pubmed/37587444
http://dx.doi.org/10.1186/s12935-023-02984-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433610/
https://www.ncbi.nlm.nih.gov/pubmed/37587444
http://dx.doi.org/10.1186/s12935-023-02984-w

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