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Role of miR‑let‑7c‑5p/c‑myc signaling axis in the committed differentiation of leukemic THP‑1 cells into monocytes/macrophages

In a preliminary experiment, it was found that c-myc expression was decreased following the differentiation of THP-1 cells into monocytes/macrophages induced by phorbol 12-myristate 13 acetate (PMA) + lipopolysaccharide (LPS) + interferon (IFN)-γ. The expression of miR-let-7c-5p was then found to be...

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Detalles Bibliográficos
Autores principales: Sun, Ruijing, Wang, Chaozhe, Wang, Yufang, Wu, Yunhua, Du, Pengchao, Sun, Xiaolin, Li, Qing, Bi, Kehong, Jiang, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433716/
https://www.ncbi.nlm.nih.gov/pubmed/37600342
http://dx.doi.org/10.3892/ol.2023.13989