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Alleviation of hippocampal necroptosis and neuroinflammation by NecroX-7 treatment after acute seizures

Temporal lobe epilepsy (TLE) is one of the most common neurological disorders, but still one-third of patients cannot be properly treated by current medication. Thus, we investigated the therapeutic effects of a novel small molecule, NecroX-7, in TLE using both a low [Mg(2+)](o)-induced epileptiform...

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Detalles Bibliográficos
Autores principales: Roh, Yihyun, Lee, Su Bin, Kim, Minseo, Kim, Mi-Hye, Kim, Hee Jung, Cho, Kyung-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433749/
https://www.ncbi.nlm.nih.gov/pubmed/37601059
http://dx.doi.org/10.3389/fphar.2023.1187819