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Alleviation of hippocampal necroptosis and neuroinflammation by NecroX-7 treatment after acute seizures
Temporal lobe epilepsy (TLE) is one of the most common neurological disorders, but still one-third of patients cannot be properly treated by current medication. Thus, we investigated the therapeutic effects of a novel small molecule, NecroX-7, in TLE using both a low [Mg(2+)](o)-induced epileptiform...
Autores principales: | Roh, Yihyun, Lee, Su Bin, Kim, Minseo, Kim, Mi-Hye, Kim, Hee Jung, Cho, Kyung-Ok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433749/ https://www.ncbi.nlm.nih.gov/pubmed/37601059 http://dx.doi.org/10.3389/fphar.2023.1187819 |
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