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Serum IL-27 levels increase in subjects with hypothyroidism and are negatively correlated with the occurrence of nonalcoholic fatty liver disease

BACKGROUND: The level of serum interleukin-27 (IL-27) was significantly decreased in the obesity group. After injection of IL-27, obese mice showed significant weight loss,reduced fat accumulation, improved insulin resistance and hepatic steatosis.IL-27 plays a key role in the regulation of metaboli...

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Detalles Bibliográficos
Autores principales: Wen, Yahui, Zhang, Heng, Yang, Ning, Gao, Xia, Chen, Zhe, Liu, Jia, Wang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433777/
https://www.ncbi.nlm.nih.gov/pubmed/37600722
http://dx.doi.org/10.3389/fendo.2023.1173826