Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-(13)C]-gluconolactone

BACKGROUND: Telomere maintenance by telomerase reverse transcriptase (TERT) is essential for immortality in most cancers, including oligodendrogliomas. Agents that disrupt telomere maintenance such as the telomere uncapping agent 6-thio-2’-deoxyguanosine (6-thio-dG) are in clinical trials. We previo...

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Detalles Bibliográficos
Autores principales: Batsios, Georgios, Taglang, Celine, Gillespie, Anne Marie, Viswanath, Pavithra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433788/
https://www.ncbi.nlm.nih.gov/pubmed/37600229
http://dx.doi.org/10.1093/noajnl/vdad092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433788/
https://www.ncbi.nlm.nih.gov/pubmed/37600229
http://dx.doi.org/10.1093/noajnl/vdad092

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