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A Novel Conserved Linear Neutralizing Epitope on the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein

The continuous emergence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made it challenging to develop broad-spectrum prophylactic vaccines and therapeutic antibodies. Here, we have identified a broad-spectrum neutralizing antibody and its highly conserved epitop...

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Detalles Bibliográficos
Autores principales: Hua, Rong-Hong, Zhang, Shu-Jian, Niu, Bei, Ge, Jin-Ying, Lan, Ting, Bu, Zhi-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433833/
https://www.ncbi.nlm.nih.gov/pubmed/37306579
http://dx.doi.org/10.1128/spectrum.01190-23