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Single-cell RNA sequencing identifies a novel proliferation cell type affecting clinical outcome of pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is an extremely deadly neoplasm, with only a 5-year survival rate of around 9%. The tumor and its microenvironment are highly heterogeneous, and it is still unknown which cell types influence patient outcomes. METHODS: We used single-cell RNA seque...

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Detalles Bibliográficos
Autores principales: Ye, Bicheng, Wang, Qi, Zhu, Xiaofeng, Zeng, Lingling, Luo, Huiyuan, Xiong, Yan, Li, Qin, Zhu, Qinmei, Zhao, Songyun, Chen, Ting, Xie, Jingen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433893/
https://www.ncbi.nlm.nih.gov/pubmed/37601684
http://dx.doi.org/10.3389/fonc.2023.1236435