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Genome-scale metabolic model led engineering of Nothapodytes nimmoniana plant cells for high camptothecin production
Camptothecin (CPT) is a vital monoterpene indole alkaloid used in anti-cancer therapeutics. It is primarily derived from Camptotheca acuminata and Nothapodytes nimmoniana plants that are indigenous to Southeast Asia. Plants have intricate metabolic networks and use them to produce secondary metaboli...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433906/ https://www.ncbi.nlm.nih.gov/pubmed/37600193 http://dx.doi.org/10.3389/fpls.2023.1207218 |