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Genome-scale metabolic model led engineering of Nothapodytes nimmoniana plant cells for high camptothecin production

Camptothecin (CPT) is a vital monoterpene indole alkaloid used in anti-cancer therapeutics. It is primarily derived from Camptotheca acuminata and Nothapodytes nimmoniana plants that are indigenous to Southeast Asia. Plants have intricate metabolic networks and use them to produce secondary metaboli...

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Detalles Bibliográficos
Autores principales:	Murali, Sarayu, Ibrahim, Maziya, Rajendran, Hemalatha, Shagun, Shagun, Masakapalli, Shyam Kumar, Raman, Karthik, Srivastava, Smita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Plant Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433906/ https://www.ncbi.nlm.nih.gov/pubmed/37600193 http://dx.doi.org/10.3389/fpls.2023.1207218

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