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Influenza vaccine format mediates distinct cellular and antibody responses in human immune organoids

Highly effective vaccines elicit specific, robust, and durable adaptive immune responses. To advance informed vaccine design, it is critical that we understand the cellular dynamics underlying responses to different antigen formats. Here, we sought to understand how antigen-specific B and T cells we...

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Detalles Bibliográficos
Autores principales: Kastenschmidt, Jenna M., Sureshchandra, Suhas, Jain, Aarti, Hernandez-Davies, Jenny E., de Assis, Rafael, Wagoner, Zachary W., Sorn, Andrew M., Mitul, Mahina Tabassum, Benchorin, Aviv I., Levendosky, Elizabeth, Ahuja, Gurpreet, Zhong, Qiu, Trask, Douglas, Boeckmann, Jacob, Nakajima, Rie, Jasinskas, Algimantas, Saligrama, Naresha, Davies, D. Huw, Wagar, Lisa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433940/
https://www.ncbi.nlm.nih.gov/pubmed/37478854
http://dx.doi.org/10.1016/j.immuni.2023.06.019