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Interactome Analysis Identifies MSMEI_3879 as a Substrate of Mycolicibacterium smegmatis ClpC1

The prevalence of drug-resistant Mycobacterium tuberculosis infections has prompted extensive efforts to exploit new drug targets in this globally important pathogen. ClpC1, the unfoldase component of the essential ClpC1P1P2 protease, has emerged as one particularly promising antibacterial target. H...

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Detalles Bibliográficos
Autores principales: Ogbonna, Emmanuel C., Anderson, Henry R., Beardslee, Patrick C., Bheemreddy, Priyanka, Schmitz, Karl R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433963/
https://www.ncbi.nlm.nih.gov/pubmed/37341639
http://dx.doi.org/10.1128/spectrum.04548-22