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Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIβ

Enteroviruses are one of the most abundant viruses causing mild to serious acute infections in humans and also contributing to chronic diseases like type 1 diabetes. Presently, there are no approved antiviral drugs against enteroviruses. Here, we studied the potency of vemurafenib, an FDA-approved R...

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Detalles Bibliográficos
Autores principales: Laajala, Mira, Zwaagstra, Marleen, Martikainen, Mari, Nekoua, Magloire Pandoua, Benkahla, Mehdi, Sane, Famara, Gervais, Emily, Campagnola, Grace, Honkimaa, Anni, Sioofy-Khojine, Amir-Babak, Hyöty, Heikki, Ojha, Ravi, Bailliot, Marie, Balistreri, Giuseppe, Peersen, Olve, Hober, Didier, Van Kuppeveld, Frank, Marjomäki, Varpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433971/
https://www.ncbi.nlm.nih.gov/pubmed/37436162
http://dx.doi.org/10.1128/spectrum.00552-23