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Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIβ
Enteroviruses are one of the most abundant viruses causing mild to serious acute infections in humans and also contributing to chronic diseases like type 1 diabetes. Presently, there are no approved antiviral drugs against enteroviruses. Here, we studied the potency of vemurafenib, an FDA-approved R...
Autores principales: | Laajala, Mira, Zwaagstra, Marleen, Martikainen, Mari, Nekoua, Magloire Pandoua, Benkahla, Mehdi, Sane, Famara, Gervais, Emily, Campagnola, Grace, Honkimaa, Anni, Sioofy-Khojine, Amir-Babak, Hyöty, Heikki, Ojha, Ravi, Bailliot, Marie, Balistreri, Giuseppe, Peersen, Olve, Hober, Didier, Van Kuppeveld, Frank, Marjomäki, Varpu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433971/ https://www.ncbi.nlm.nih.gov/pubmed/37436162 http://dx.doi.org/10.1128/spectrum.00552-23 |
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