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Repurposing High-Throughput Screening Identifies Unconventional Drugs with Antibacterial and Antibiofilm Activities against Pseudomonas aeruginosa under Experimental Conditions Relevant to Cystic Fibrosis

Pseudomonas aeruginosa is the most common pathogen infecting cystic fibrosis (CF) lungs, causing acute and chronic infections. Intrinsic and acquired antibiotic resistance allow P. aeruginosa to colonize and persist despite antibiotic treatment, making new therapeutic approaches necessary. Combining...

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Detalles Bibliográficos
Autores principales: Di Bonaventura, Giovanni, Lupetti, Veronica, Di Giulio, Andrea, Muzzi, Maurizio, Piccirilli, Alessandra, Cariani, Lisa, Pompilio, Arianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433973/
https://www.ncbi.nlm.nih.gov/pubmed/37306577
http://dx.doi.org/10.1128/spectrum.00352-23