Cargando…

Mouse Liver-Expressed Shiftless Is an Evolutionarily Conserved Antiviral Effector Restricting Human and Murine Hepaciviruses

Mice are refractory to infection with human-tropic hepatitis C virus (HCV), although distantly related rodent hepaciviruses (RHV) circulate in wild rodents. To investigate whether liver intrinsic host factors can exhibit broad restriction against these distantly related hepaciviruses, we focused on...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yudi, Kinast, Volker, Sheldon, Julie, Frericks, Nicola, Todt, Daniel, Zimmer, Matthias, Caliskan, Neva, Brown, Richard J. P., Steinmann, Eike, Pietschmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433982/
https://www.ncbi.nlm.nih.gov/pubmed/37341610
http://dx.doi.org/10.1128/spectrum.01284-23