Coevolution of furA-Regulated Hyper-Inflammation and Mycobacterial Resistance to Oxidative Killing through Adaptation to Hydrogen Peroxide

Mycobacterium tuberculosis (Mtb) is highly resistant to host oxidative killing. We hypothesized that the evolutionary adaptation of M. smegmatis to hydrogen peroxide (H(2)O(2)) would endow the nonpathogenic Mycobacterium persistent in a host. In the study, we screened a highly H(2)O(2)-resistant str...

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Detalles Bibliográficos
Autores principales: Fan, Xin, Zhao, Bei, Zhang, Weishan, Li, Ning, Mi, Kaixia, Wang, Beinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433983/
https://www.ncbi.nlm.nih.gov/pubmed/37358434
http://dx.doi.org/10.1128/spectrum.05367-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433983/
https://www.ncbi.nlm.nih.gov/pubmed/37358434
http://dx.doi.org/10.1128/spectrum.05367-22

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