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Coevolution of furA-Regulated Hyper-Inflammation and Mycobacterial Resistance to Oxidative Killing through Adaptation to Hydrogen Peroxide
Mycobacterium tuberculosis (Mtb) is highly resistant to host oxidative killing. We hypothesized that the evolutionary adaptation of M. smegmatis to hydrogen peroxide (H(2)O(2)) would endow the nonpathogenic Mycobacterium persistent in a host. In the study, we screened a highly H(2)O(2)-resistant str...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433983/ https://www.ncbi.nlm.nih.gov/pubmed/37358434 http://dx.doi.org/10.1128/spectrum.05367-22 |