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Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents

Mpox virus (formerly monkeypox virus [MPXV]) is a neglected zoonotic pathogen that caused a worldwide outbreak in May 2022. Given the lack of an established therapy, the development of an anti-MPXV strategy is of vital importance. To identify drug targets for the development of anti-MPXV agents, we...

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Detalles Bibliográficos
Autores principales: Hishiki, Takayuki, Morita, Takeshi, Akazawa, Daisuke, Ohashi, Hirofumi, Park, Eun-Sil, Kataoka, Michiyo, Mifune, Junki, Shionoya, Kaho, Tsuchimoto, Kana, Ojima, Shinjiro, Azam, Aa Haeruman, Nakajima, Shogo, Kawahara, Madoka, Yoshikawa, Tomoki, Shimojima, Masayuki, Kiga, Kotaro, Maeda, Ken, Suzuki, Tadaki, Ebihara, Hideki, Takahashi, Yoshimasa, Watashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434032/
https://www.ncbi.nlm.nih.gov/pubmed/37409948
http://dx.doi.org/10.1128/spectrum.00566-23