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FAM46C Is an Interferon-Stimulated Gene That Inhibits Lentiviral Particle Production by Modulating Autophagy

FAM46C is a multiple myeloma (MM) tumor suppressor whose function is only starting to be elucidated. We recently showed that in MM cells FAM46C triggers apoptosis by inhibiting autophagy and altering intracellular trafficking and protein secretion. To date, both a physiological characterization of F...

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Detalles Bibliográficos
Autores principales: Mancino, Marilena, Lai, Giancarlo, De Grossi, Federica, Cuomo, Alessandro, Manganaro, Lara, Butta, Giacomo M., Ferrari, Ivan, Vicenzi, Elisa, Poli, Guido, Pesce, Elisa, Oliveto, Stefania, Biffo, Stefano, Manfrini, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434054/
https://www.ncbi.nlm.nih.gov/pubmed/37358411
http://dx.doi.org/10.1128/spectrum.05211-22