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Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance

Campylobacter jejuni is a bacterium that is commonly present in the intestinal tracts of animals. It is also a major foodborne pathogen that causes gastroenteritis in humans. The most predominant and clinically important multidrug efflux system in C. jejuni is the CmeABC (Campylobacter multidrug eff...

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Detalles Bibliográficos
Autores principales: Zhang, Zhemin, Lizer, Nicholas, Wu, Zuowei, Morgan, Christopher E., Yan, Yuqi, Zhang, Qijing, Yu, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434076/
https://www.ncbi.nlm.nih.gov/pubmed/37289051
http://dx.doi.org/10.1128/spectrum.01197-23