Methylxanthines Modulate Circadian Period Length Independently of the Action of Phosphodiesterase

In Neurospora crassa, caffeine and other methylxanthines are known to inhibit phosphodiesterase (PDE) activity, leading to augmented cAMP levels. In this organism, it has also been shown that the addition of these drugs significantly lengthens the circadian period, as seen by conidiation rhythms. Ut...

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Detalles Bibliográficos
Autores principales: Olivares-Yañez, Consuelo, Alessandri, María P., Salas, Loreto, Larrondo, Luis F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434132/
https://www.ncbi.nlm.nih.gov/pubmed/37272789
http://dx.doi.org/10.1128/spectrum.03727-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434132/
https://www.ncbi.nlm.nih.gov/pubmed/37272789
http://dx.doi.org/10.1128/spectrum.03727-22

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