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Gallium Nitrate Enhances Antimicrobial Activity of Colistin against Klebsiella pneumoniae by Inducing Reactive Oxygen Species Accumulation

Klebsiella pneumoniae, a pathogen of critical clinical concern, urgently demands effective therapeutic options owing to its drug resistance. Polymyxins are increasingly regarded as a last-line therapeutic option for the treatment of multidrug-resistant (MDR) Gram-negative bacterial infections. Howev...

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Detalles Bibliográficos
Autores principales: Guo, Mingjuan, Tian, Ping, Li, Qingqing, Meng, Bao, Ding, Yuting, Liu, Yanyan, Li, Yasheng, Yu, Liang, Li, Jiabin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434156/
https://www.ncbi.nlm.nih.gov/pubmed/37272820
http://dx.doi.org/10.1128/spectrum.00334-23