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Establishment of a Novel Detection Platform for Clostridioides difficile Toxin Genes Based on Orthogonal CRISPR

Clostridioides difficile is one of the leading pathogens causing nosocomial infection. The infection can range from mild to severe, and rapid identification is pivotal for early clinical diagnosis and appropriate treatment. Here, a genetic testing platform for toxins, referred to as OC-MAB (orthogon...

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Detalles Bibliográficos
Autores principales: Jiang, Tong, Hu, Xinyi, Shen, Jilu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434169/
https://www.ncbi.nlm.nih.gov/pubmed/37378559
http://dx.doi.org/10.1128/spectrum.01886-23