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A Phase 2 Randomized Trial Evaluating the Antiviral Activity and Safety of the Direct-Acting Antiviral Bemnifosbuvir in Ambulatory Patients with Mild or Moderate COVID-19 (MOONSONG Study)

Bemnifosbuvir is an oral antiviral drug with a dual mechanism of action targeting viral RNA polymerase, with in vitro activity against SARS-CoV-2. We conducted a phase 2, double-blind study evaluating the antiviral activity, safety, efficacy, and pharmacokinetics of bemnifosbuvir in ambulatory patie...

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Detalles Bibliográficos
Autores principales: Boffito, Marta, Dolan, Eamon, Singh, Karishma, Holmes, William, Wildum, Steffen, Horga, Arantxa, Pietropaolo, Keith, Zhou, Xiao-Jian, Clinch, Barry, Collinson, Neil, Ukachukwu, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434175/
https://www.ncbi.nlm.nih.gov/pubmed/37338393
http://dx.doi.org/10.1128/spectrum.00077-23