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The C(2)H(2)-Type Transcription Factor ZfpA, Coordinately with CrzA, Affects Azole Susceptibility by Regulating the Multidrug Transporter Gene atrF in Aspergillus fumigatus

The incidence of invasive aspergillosis caused by Aspergillus fumigatus has risen steadily over the past few decades due to the limited effective treatment options and the emergence of antifungal-resistant isolates. In clinic-isolated A. fumigatus, the azole resistance mechanism is primarily caused...

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Detalles Bibliográficos
Autores principales: Li, Yeqi, Dai, Mengyao, Lu, Ling, Zhang, Yuanwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434176/
https://www.ncbi.nlm.nih.gov/pubmed/37318356
http://dx.doi.org/10.1128/spectrum.00325-23