Gamma Irradiation-Inactivated Respiratory Syncytial Virus Vaccine Provides Protection but Exacerbates Pulmonary Inflammation by Switching from Prefusion to Postfusion F Protein

Respiratory syncytial virus (RSV) is a common respiratory pathogen that causes lower respiratory diseases among infants and elderly people. Moreover, formalin-inactivated RSV (FI-RSV) vaccine induces serious enhanced respiratory disease (ERD). Radiation has been investigated as an alternative approa...

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Detalles Bibliográficos
Autores principales: Chen, Fengjia, Park, Hae-Ran, Ji, Hyun Jung, Kwon, Yeongkag, Kim, Min-Kyu, Song, Joon Young, Ahn, Ki Bum, Seo, Ho Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434263/
https://www.ncbi.nlm.nih.gov/pubmed/37272801
http://dx.doi.org/10.1128/spectrum.01358-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434263/
https://www.ncbi.nlm.nih.gov/pubmed/37272801
http://dx.doi.org/10.1128/spectrum.01358-23

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