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The role of p53 in anti-tumor immunity and response to immunotherapy

p53 is a transcription factor that regulates the expression of genes involved in tumor suppression. p53 mutations mediate tumorigenesis and occur in approximately 50% of human cancers. p53 regulates hundreds of target genes that induce various cell fates including apoptosis, cell cycle arrest, and D...

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Detalles Bibliográficos
Autores principales: Carlsen, Lindsey, Zhang, Shengliang, Tian, Xiaobing, De La Cruz, Arielle, George, Andrew, Arnoff, Taylor E., El-Deiry, Wafik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434531/
https://www.ncbi.nlm.nih.gov/pubmed/37602328
http://dx.doi.org/10.3389/fmolb.2023.1148389