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The role of p53 in anti-tumor immunity and response to immunotherapy
p53 is a transcription factor that regulates the expression of genes involved in tumor suppression. p53 mutations mediate tumorigenesis and occur in approximately 50% of human cancers. p53 regulates hundreds of target genes that induce various cell fates including apoptosis, cell cycle arrest, and D...
Autores principales: | Carlsen, Lindsey, Zhang, Shengliang, Tian, Xiaobing, De La Cruz, Arielle, George, Andrew, Arnoff, Taylor E., El-Deiry, Wafik S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434531/ https://www.ncbi.nlm.nih.gov/pubmed/37602328 http://dx.doi.org/10.3389/fmolb.2023.1148389 |
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