Development of an in vitro aggregation assay for long synthetic polypeptide, amyloidogenic gelsolin fragment AGelD187N 173–242

Aggregation of the gelsolin protein fragment is the hallmark of the hereditary systemic disease gelsolin amyloidosis. As with other protein misfolding diseases, there is an urgent need for efficient disease-modifying treatment for gelsolin amyloidosis. The formation of amyloids can be reproduced by...

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Detalles Bibliográficos
Autores principales: Leimu, Laura, Haavisto, Oskar, Nesati, Victor, Holm, Patrik, Haapalinna, Antti, Salbo, Rune, Pesonen, Ullamari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434866/
https://www.ncbi.nlm.nih.gov/pubmed/37590229
http://dx.doi.org/10.1371/journal.pone.0290179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434866/
https://www.ncbi.nlm.nih.gov/pubmed/37590229
http://dx.doi.org/10.1371/journal.pone.0290179

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