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E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response

Ubiquitin-dependent control of mitochondrial dynamics is important for protein quality and neuronal integrity. Mitofusins, mitochondrial fusion factors, can integrate cellular stress through their ubiquitylation, which is carried out by multiple E3 enzymes in response to many different stimuli. Howe...

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Detalles Bibliográficos
Autores principales: Anton, Vincent, Buntenbroich, Ira, Simões, Tânia, Joaquim, Mariana, Müller, Leonie, Buettner, Reinhard, Odenthal, Margarete, Hoppe, Thorsten, Escobar-Henriques, Mafalda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434984/
https://www.ncbi.nlm.nih.gov/pubmed/37595558
http://dx.doi.org/10.1016/j.molcel.2023.07.021