A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes

Mouse models of CLN3 Batten disease, a rare lysosomal storage disorder with no cure, have improved our understanding of CLN3 biology and therapeutics through their ease of use and a consistent display of cellular pathology. However, the translatability of murine models is limited by disparities in a...

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Detalles Bibliográficos
Autores principales: Swier, Vicki J., White, Katherine A., Johnson, Tyler B., Wang, Xiaojun, Han, Jimin, Pearce, David A., Singh, Ruchira, Drack, Arlene V., Pfeifer, Wanda, Rogers, Christopher S., Brudvig, Jon J., Weimer, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434985/
https://www.ncbi.nlm.nih.gov/pubmed/37305926
http://dx.doi.org/10.1242/dmm.050038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434985/
https://www.ncbi.nlm.nih.gov/pubmed/37305926
http://dx.doi.org/10.1242/dmm.050038

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