A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression

N(6)-methyladenosine (m(6)A) methylation of RNA by the methyltransferase complex (MTC), with core components including METTL3–METTL14 heterodimers and Wilms’ tumor 1-associated protein (WTAP), contributes to breast tumorigenesis, but the underlying regulatory mechanisms remain elusive. Here, we iden...

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Detalles Bibliográficos
Autores principales: Yan, Chaojun, Xiong, Jingjing, Zhou, Zirui, Li, Qifang, Gao, Chuan, Zhang, Mengyao, Yu, Liya, Li, Jinpeng, Hu, Ming-Ming, Zhang, Chen-Song, Cai, Cheguo, Zhang, Haojian, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435237/
https://www.ncbi.nlm.nih.gov/pubmed/37589705
http://dx.doi.org/10.7554/eLife.87283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435237/
https://www.ncbi.nlm.nih.gov/pubmed/37589705
http://dx.doi.org/10.7554/eLife.87283

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