Lipidation states orchestrate CLICK-III/CaMKIγ's stepwise association with Golgi and rafts-enriched membranes and specify its functional coupling to STEF-Rac1-dependent neurite extension

CLICK-III/CaMKIγ is a lipid-anchored neuronal isoform of multifunctional Ca(2+)/calmodulin-dependent protein kinases, which mediates BDNF-dependent dendritogenesis in cultured cortical neurons. We found that two distinct lipidation states of CaMKIγ, namely, prenylation and palmitoylation, controlled...

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Detalles Bibliográficos
Autores principales: Ageta-Ishihara, Natsumi, Takemoto-Kimura, Sayaka, Kondo, Yayoi, Okamura, Michiko, Bito, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435254/
https://www.ncbi.nlm.nih.gov/pubmed/37601281
http://dx.doi.org/10.3389/fncel.2023.1204302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435254/
https://www.ncbi.nlm.nih.gov/pubmed/37601281
http://dx.doi.org/10.3389/fncel.2023.1204302

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