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Establishment of a human microbiome- and immune system-reconstituted dual-humanized mouse model

Humanized mice are widely used to study the human immune system in vivo and investigate therapeutic targets for various human diseases. Immunodeficient NOD/Shi-scid-IL2rγ(null) (NOG) mice transferred with human hematopoietic stem cells are a useful model for studying human immune systems and analyzi...

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Detalles Bibliográficos
Autores principales: Ka, Yuyo, Ito, Ryoji, Nozu, Ryoko, Tomiyama, Kayo, Ueno, Masami, Ogura, Tomoyuki, Takahashi, Riichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435363/
https://www.ncbi.nlm.nih.gov/pubmed/37019665
http://dx.doi.org/10.1538/expanim.23-0025