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RabGAP AS160/TBC1D4 deficiency increases long-chain fatty acid transport but has little additional effect on obesity and metabolic syndrome in ADMSCs-derived adipocytes of morbidly obese women

The Akt substrate of 160 kDa (AS160), also known as TBC1 domain family member 4 (TBC1D4), represents a crucial regulator of insulin-stimulated glucose uptake in skeletal muscle and adipose tissue. Recent evidence suggests that AS160/TBC1D4 may also control the cellular entry of long-chain fatty acid...

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Detalles Bibliográficos
Autores principales: Mikłosz, Agnieszka, Łukaszuk, Bartłomiej, Supruniuk, Elżbieta, Grubczak, Kamil, Kusaczuk, Magdalena, Chabowski, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435366/
https://www.ncbi.nlm.nih.gov/pubmed/37602323
http://dx.doi.org/10.3389/fmolb.2023.1232159