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Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity

Obesity contributes substantially to the global burden of disease and has a significant heritable component. Recent large-scale exome sequencing studies identified several genes in which rare, protein-coding variants have large effects on adult body mass index (BMI). Here we extended such work by pe...

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Detalles Bibliográficos
Autores principales: Kaisinger, Lena R., Kentistou, Katherine A., Stankovic, Stasa, Gardner, Eugene J., Day, Felix R., Zhao, Yajie, Mörseburg, Alexander, Carnie, Christopher J., Zagnoli-Vieira, Guido, Puddu, Fabio, Jackson, Stephen P., O’Rahilly, Stephen, Farooqi, I. Sadaf, Dearden, Laura, Pantaleão, Lucas C., Ozanne, Susan E., Ong, Ken K., Perry, John R.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435378/
https://www.ncbi.nlm.nih.gov/pubmed/37601970
http://dx.doi.org/10.1016/j.xgen.2023.100362